4-Iodobenzylzinc bromide
4-Iodobenzylzinc bromide
CAS: 352530-30-4
Molecular Formula: C7H6BrIZn
4-Iodobenzylzinc bromide - Names and Identifiers
| Name | 4-Iodobenzylzinc bromide |
| Synonyms | 4-Iodobenzylzinc bromide 4-Iodobenzylzinc bromide 0.5 M in Tetrahydrofuran |
| CAS | 352530-30-4 |
4-Iodobenzylzinc bromide - Physico-chemical Properties
| Molecular Formula | C7H6BrIZn |
| Molar Mass | 362.32101 |
| Density | 1.035g/mLat 25°C |
| Boling Point | 65°C |
| Flash Point | 1°F |
4-Iodobenzylzinc bromide - Risk and Safety
| Risk Codes | R11 - Highly Flammable R14 - Reacts violently with water R19 - May form explosive peroxides R34 - Causes burns |
| Safety Description | S16 - Keep away from sources of ignition. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
| UN IDs | UN 2924 3/PG 2 |
| WGK Germany | 1 |
4-Iodobenzylzinc bromide - Introduction
4-Iodobenzylzinc bromide(4-Iodobenzylzinc bromide) is an organic zinc compound. It has the formula C7H6BrIZn and is usually present in powder form.
4-Iodobenzylzine bromide has a wide range of applications in the field of organic synthesis. It can be used as a condensation reagent to participate in inorganic chemical addition reactions of alkenes and alkynes, such as Grignard reactions and Sonogashira reactions. In addition, it can also be used in C- C bond-forming reactions and the synthesis of zinc-based reagents.
A common method for preparing 4-iodobenzylzinc bromide is to heat benzyl iodide and zinc chloride in a polar solvent such as dimethylformamide (DMF) or dimethyl sulfoxide (DMSO). After completion of the reaction, the product was precipitated from the solution by addition of ammonium chloride.
When using and handling 4-Iodobenzylzinc bromide, you need to pay attention to the following safety precautions:
1. 4-Iodobenzylzinc bromide is an organic zinc compound, which has certain toxicity and should be operated under strict ventilation conditions.
2. In case of contact with skin or inhalation, rinse with water immediately and seek medical help.
3. avoid contact with strong oxidants and acidic substances to avoid dangerous reactions.
4. storage should be kept in a cool, dry place, avoid contact with air and moisture.
Although 4-Iodobenzylzine bromide has some potential hazards, when used and handled correctly in the laboratory, it can become an important reagent in organic synthesis. To ensure safety, please carefully read and follow the relevant safety instructions and operating procedures before use.
4-Iodobenzylzine bromide has a wide range of applications in the field of organic synthesis. It can be used as a condensation reagent to participate in inorganic chemical addition reactions of alkenes and alkynes, such as Grignard reactions and Sonogashira reactions. In addition, it can also be used in C- C bond-forming reactions and the synthesis of zinc-based reagents.
A common method for preparing 4-iodobenzylzinc bromide is to heat benzyl iodide and zinc chloride in a polar solvent such as dimethylformamide (DMF) or dimethyl sulfoxide (DMSO). After completion of the reaction, the product was precipitated from the solution by addition of ammonium chloride.
When using and handling 4-Iodobenzylzinc bromide, you need to pay attention to the following safety precautions:
1. 4-Iodobenzylzinc bromide is an organic zinc compound, which has certain toxicity and should be operated under strict ventilation conditions.
2. In case of contact with skin or inhalation, rinse with water immediately and seek medical help.
3. avoid contact with strong oxidants and acidic substances to avoid dangerous reactions.
4. storage should be kept in a cool, dry place, avoid contact with air and moisture.
Although 4-Iodobenzylzine bromide has some potential hazards, when used and handled correctly in the laboratory, it can become an important reagent in organic synthesis. To ensure safety, please carefully read and follow the relevant safety instructions and operating procedures before use.
Last Update：2024-04-10 22:29:15
